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Pharmaceutical Engineering
Administered By: Otto H. York Department of Chemical, Biological and Pharmaceutical Engineering
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Administration
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Program Director Armenant

Administration
Program Director Piero M. Armenante
 

Program Objective:
The Master of Science Program in Pharmaceutical Engineering is a program developed and administered by the Otto H. York Department of Chemical, Biological and Pharmaceutical Engineering at NJIT. The primary objective of the program is to educate professionals and provide them with the skills required to work in the pharmaceutical field, with particular emphasis on the engineering aspects of drug manufacturing, pharmaceutical production, pharmaceutical development, and pharmaceutical operations.

The pharmaceutical/medical technology industry is the largest manufacturing industry in New Jersey. New Jersey is home to the headquarters of more global pharmaceutical and medical technology companies than any other state in the country, or any single country throughout the world. NJIT's M.S. program in Pharmaceutical Engineering provides the intellectual climate and the necessary tools needed to prepare students for positions and career advancement within the industry, based on the rigorous technological requirements of this highly regulated work environment.

The program is designed to provide opportunities for specialization in such areas as pharmaceutical processing and manufacturing, validation and regulatory issues in the pharmaceutical industry, pharmaceutical facility design, pharmaceutical packaging technology, reaction engineering for pharmaceutical production, pharmaceutical separation processes, pharmacokinetics and drug delivery, molecular modeling for drug discovery, pharmaceutical synthesis, fluid mixing in the pharmaceutical industry, instrumental analysis, and industrial quality control.

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Master of Science in Pharmaceutical Engineering 5
 
Master of Science in Pharmaceutical Engineering

Admission Requirements:
An undergraduate degree in chemical engineering or, in most cases, mechanical engineering, with a cumulative grade point average (GPA) of at least 3.0 on a 4.0 scale is usually required. Applicants with: (1) a science degree, (2) an engineering degree in a discipline other than chemical or mechanical engineering, or (3) a GPA below 3.0 but at least 2.8, may be conditionally admitted to the program. Conditions may involve completion of a bridge program designed on a case-by-case basis, and typically requiring taking extra bridge courses, as further explained below. Depending on the background of the student, admission conditions may additionally require taking undergraduate courses (e.g., chemistry) or graduate courses. Bridge and undergraduate courses do not count toward degree credit; graduate-level courses do.

Submission of Graduate Record Examination (GRE) scores is encouraged in all cases, and required of those seeking financial support and those whose last prior degree is from an institution outside the United States. International students must also submit scores from the Test of English as a Foreign Language (TOEFL). According to university policy, a minimum TOEFL score of 550 (pencil and paper) and 213 (computer-based) is required.

The admission requirements described above can be partially relaxed for applicants with significant industrial experience in the pharmaceutical industry (5+ years). The admission requirements for such candidates will be established on a case-by-case basis, and will be determined through an interview with the prospective student and the submission of letters of support attesting the level of experience attained.

Bridge Program:
The Pharmaceutical Engineering program has been designed so that applicants with different backgrounds can be admitted. Nevertheless, the program is strongly oriented toward the engineering component of "Pharmaceutical Engineering". In addition, since the pharmaceutical industry is a chemistry-based industry a chemical engineering background is the most appropriate to enter the program (mechanical engineers are also generally well prepared to enter the program). This implies that students who have a science background (e.g., a chemistry or pharmacy B.S. degree) or an engineering degree in a discipline other than chemical or, possibly, mechanical engineering, may be required to take a bridge program. Depending on the background of the applicant this bridge program may consist of up to (but generally speaking less, at least for students with engineering degrees) three 3-credit courses (PhEn 500, PhEn 501 and PhEn 502) specifically designed to provide non-chemical engineers with the necessary prerequisites to enter the program. The bridge courses cover a variety of topics, such as differential equations, statistics and business math (PhEn 500), mass balances, thermodynamics, and chemical kinetics (PhEn 501), and fluid flow, heat transfer and mass transfer (PhEn 502).

A grade point average of at least 3.0 must be achieved in the bridge courses. Students should pay special attention to the successful completion of the bridge courses, since failure to do so may preclude them from enrolling in regular PhEn courses. PhEn 500 and PhEn 501 can and should be taken concurrently. Both courses are only offered in the fall semester. Successful completion of both PhEn 500 and PhEn 501 is required to enroll in PhEn 502, which is offered only in the spring semester. Students must take the bridge courses before taking any other PhEn courses, with the exception of PhEn 601 and PhEn 604, which can be taken concurrently with the bridge courses. As already mentioned, admission conditions may also include taking additional undergraduate or graduate courses, if needed.

Degree Requirements:
The Master of Science in Pharmaceutical Engineering is a 30-credit program structured along two different tracks. The two tracks have a common 15-credit core. Each track has an additional 6-credit track-core, as described below. Each track has 9 credits of electives selected by the student in consultation with, and subject to, the approval of the program advisor for the selected track

Students have the option of fulfilling 6 of the 9 credits of electives by doing a Master's Thesis. The thesis option is primarily, but not exclusively, meant for full-time students. Full-time students receiving support (full or partial) must complete a Master's Thesis. Part-time students working in the pharmaceutical industry are encouraged to pursue a Master's Thesis, possibly conducted at their site and in collaboration with their supervisor.

Students must maintain an overall cumulative grade point average of at least 3.0 throughout their academic career. Students are certified for graduation only if they:

  • achieve an OVERALL cumulative grade point average of at least 3.0; and

  • achieve a grade point average of at least 3.0 in the required seven CORE COURSES; and
    achieve a grade point average of at least 3.0 in the BRIDGE COURSES.

Students may not repeat a course without approval of both the Program Director and the Office of Graduate Studies, located in the East Building, Suite 140. The grade received in a repeated course will replace the original grade in the calculation of the cumulative grade point average, although the first grade will still appear on the transcript. A MAXIMUM OF TWO COURSES MAY BE REPEATED. Students who receive an F in a course are required to repeat the course.

Program of Study:
The program of study includes common core courses, track-specific core courses, elective courses, and, if the students so chooses, a thesis (in lieu of some elective courses), as specified below. The common core courses cover a variety of topics ranging from drug dosage forms to drug manufacturing processes, validation and regulatory issues, design criteria and unit operations for pharmaceutical processes, pharmacokinetics and drug delivery.

The program has two tracks, i.e.:

  • Track 1 - Process Development and Design for Drug Substance Manufacturing. This track is focused on the engineering aspects of chemical reaction and separation processes required for the manufacturing of active pharmaceutical ingredients.

  • Track 2 - Process Development and Design for Drug Product Manufacturing. This track is focused on the engineering aspects of processes required for the manufacturing of final drug products.

All students must take the same five (5) common core courses as well as the two (2) track-specific core courses for the track that they have selected. Irrespective of the track selected, the total number of core courses (7) and the corresponding core credits (21) are the same for both tracks.

Course Requirements:

  • Five (5) core courses common to both tracks (3 credits each; 15 credits total), as follows:

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  PhEn 601 Principles of Pharmaceutical Engineering (3 credits )
  PhEn 603 Pharmaceutical Unit Operations: Processing of Liquid and Dispersed Phase Systems (3 credits )
  PhEn 604 Validation and Regulatory Issues in the Pharmaceutical Industry (3 credits )
  PhEn 606Pharmaceutical Unit Operations: Solids Processing (3 credits)
  PhEn 618Principles of Pharmacokinetics and Drug Delivery (3 credits)
  • Two (2) additional core courses specific to the track selected (3 credits each; 6 credits total), as follows:

Track 1 � Process Development and Design for Drug Substance Manufacturing:

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  PhEn 612Pharmaceutical Reaction Engineering (3 credits)
  PhEn 614Pharmaceutical Separation Processes (3 credits)
Track 2 � Process Development and Design for Drug Product Manufacturing: phen602,phen605
  PhEn 602Pharmaceutical Facility Design (3 credits)
  PhEn 605Pharmaceutical Packaging Technology (3 credits)
  • Three (3) additional elective courses (3 credits each) selected from the list of available courses (9 credits total). Electives can be selected from among pharmaceutical engineering courses (such as the courses in the track not chosen by the student), as well as appropriate courses in disciplines such as chemical engineering, mechanical engineering, industrial engineering, biomedical engineering, chemistry, biology, mathematics, and others. A partial list of electives is provided below.

M.S. THESIS:
Students who are required, or choose, to do a thesis must take 6 credits of PhEn 701 (Master's Thesis) in lieu of 6 credits worth of elective courses. Part-time students working in the pharmaceutical industry are eligible and encouraged to pursue the thesis option. NJIT requires that a student must register for thesis during the last semester before graduation, even if this requires taking addition thesis credit beyond the required 6.


List of Elective Courses:
The following is a non-exhaustive, partial list of courses that can be taken as elective courses [all courses are 3-credits unless otherwise stated]:

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  PhEn 602Pharmaceutical Facility Design (3 credits)
  PhEn 605Pharmaceutical Packaging Technology (3 credits)
  PhEn 612Pharmaceutical Reaction Engineering (3 credits)
  PhEn 614Pharmaceutical Separation Processes (3 credits)
  PHEN616 
  PhEn 700Master's Thesis (3 credits)
  PhEn 701Master's Thesis (6 credits)
  PhEn 702 Selected Topics in Pharmaceutical Engineering (3 credits )
  PhEn 725 Independent Study (3 credits)
  BME 627Introduction to Biomedical Engineering (3 credits)
  BME 672Biomaterials (3 credits)
  BME 675 Computer Methods in Biomedical Engineering (3 credits )
  ChE 611Thermodynamics (3 credits)
  ChE 624Transport Phenomena I (3 credits)
  ChE 626Mathematical Methods in Chemical Engineering (3 credits)
  ChE 628Biochemical Engineering (3 credits)
  ChE 656Industrial Catalysis: Fundamentals & Applications (3 credits)
  ChE 675Statistical Thermodynamics (3 credits)
  ChE 681Polymerization-Principles and Practice (3 credits)
  Chem 601Special Topics in Chemistry I (3 credits)
  Chem 602Advanced Organic Chemistry II: Reactions (3 credits)
  Chem 603Advanced Organic Chemistry Laboratory (3 credits)
  Chem 605Advanced Organic Chemistry I: Structure (3 credits)
  Chem 606Physical Organic Chemistry (3 credits)
  Chem 644Fundamentals of Adhesion (3 credits)
  Chem 658Advanced Physical Chemistry (3 credits)
  Chem 661 Instrumental Analysis Laboratory (3 credits)
  Chem 664Advanced Analytical Chemistry (3 credits)
  Chem 673Biochemistry (3 credits)
  CS 610Data Structures and Algorithms (3 credits)
  CS 631Data Management System Design (3 credits)
  EM 636Project Management (3 credits)
  EM 637Project Control (3 credits)
  EM 640Distribution Logistics (3 credits)
  IE 604Advanced Engineering Statistics (3 credits)
  IE 605Engineering Reliability (3 credits)
  IE 618Engineering Cost and Production Economics (3 credits)
  IE 672Industrial Quality Control (3 credits)
  IE 673Total Quality Management (3 credits)
  IE 674Quality Maintenance and Support Systems (3 credits)
  IE 704Sequencing and Scheduling (3 credits)
  ME 624Microlevel Modeling in Particle Technology (3 credits)
  ME 664Experiments and Simulations in Particle Technology (3 credits)
  MnE 601Computerized Manufacturing Systems (3 credits)
  MnE 602Flexible and Computer Integrated Manufacturing (3 credits)

Student Involvement in Research:
In addition to taking courses, students have the opportunity to work, one-on-one, with faculty members on research projects in areas of common interest, allowing maximum flexibility for independent work, and providing students with valuable research experience. Students have the option to complete a Master's thesis. PART-TIME STUDENTS WORKING IN THE PHARMACEUTICAL INDUSTRY ARE ENCOURAGED TO PURSUE A MASTER'S THESIS, POSSIBLY CONDUCTED AT THEIR SITE AND IN COLLABORATION WITH THEIR SUPERVISOR.

Qualified and research oriented students have the option of continuing their studies at NJIT by pursuing a Ph.D. in chemical engineering, industrial engineering, chemistry, or related disciplines. The NJIT-Industry Collaborative Ph.D. Program allows greater flexibility to industrial students who are interested in pursuing their Ph.D. while working full-time in industry.

For further information please contact:

Piero M. Armenante, Ph.D.
NJIT, Otto H. York Department of Chemical Biological & Pharmaceutical Engineering, 120 YCEES
University Heights, Newark, NJ 07102-1982
Phone: 973-596-3548
Fax: 973-596-8436
Email: piero.armenante@njit.edu
 


Catalog and curricula information approved by the relevant academic department.