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BME 101 - Introduction to Biomedical Engineering (1-0-0)
This course is open only to freshmen and new transfer students. Faculty members describe their research in biomedical engineering.
BME 105 - Introduction to Human Physiology I (2-0-2)
This course is open only to freshmen and transfer students. An overview of human physiology is presented as an introduction to subsequent core courses in the Biomedical Engineering curriculum. Not intended to be an exhaustive review of physiology, the course will instead emphasize key examples that highlight understanding of the interaction between the biomedical and engineering worlds. This course is the first of two freshman courses; this one will focus on cellular and neural-system basic physiology. Effective From: Fall 2006
BME 106 - Introduction to Human Physiology II (1-0-1)
Prerequisite: BME 105. This course is open only to freshmen and transfer students. An overview of human physiology is presented as an introduction to subsequent core courses in the Biomedical Engineering curriculum. Not intended to be an exhaustive review of physiology, the course will instead emphasize key examples that highlight understanding of the interaction between the biomedical and engineering worlds. This course is the first of two freshman courses; this one will focus on basic physiology of respiratory and cardiovascular systems. Effective From: Spring 2007
BME 301 - Electrical Fundamentals of Biomedical Engineering (1-3-3)
Prerequisites: Math 111, Math 112, Phys 111, Phys 121. Course lectures and laboratories will address important issues for biomedical engineers at the introductory level; covering the origins of bio-electric signals and the instrumentation involved in collection of biopotentials from the electrodes to processing of the signals on the computer. Some other topics included are the transducers/sensors and modern engineering software used in bio-instrumentation. Laboratory work will provide hands-on experience in all of these topics. The course will also address practical issues in design of medical devices such as noise, resolution, linearity, and saturation. This course is offered in Studio format that involves the integration of lectures and labs into one highly participatory structure. Effective From: Fall 2008
BME 302 - Mechanical Fundamentals of Biomedical Engineering (1-3-3)
Prerequisites: Math 111, Math 112, Phys 111, Phys 121. BME 301 is not a prerequisite. The format is identical to that of BME 301. Course lectures and laboratories will address important issues covering the mechanical fundamentals that are important bases for later learning experiences. This course introduces the students to biomaterials (tissues), biomechanics (forces and motion), biofluids and biostatistics, and then integrates them with a final design project on neuromuscular engineering. Effective From: Fall 2008
BME 303 - Biological and Chemical Foundations of Biomedical Engineering (3-0-3)
Prerequisites: Chem 126 and Phys 121. This course covers organic chemistry, biochemistry and cellular mechanics in sufficient depth to give biomedical engineering students a strong enough background for them to understand the introductory aspects of biomedical engineering, which focus on the application of engineering principles to medicine and surgery.
BME 310 - Biomedical Computing (3-1-3)
Prerequisite: BME 301. This course covers the application of digtal signal processing to biomedical problems. Labview, a graphical programming language common in engineering, is used for both signal acquisition and processing. Applications include analysis of the electrocardiogram and other electrical signals generated by the body. Effective From: Spring 2008
BME 311 - Co-op Work Experience (3 additive credits)
Prerequisites: completion of sophomore year, approval of department, and permission of Career Development Services. Students gain major-related work experience and reinforcement of their academic program. Work assignments facilitated by the co-op office and approved by the department. Mandatory participation in seminars and completion of a report.
BME 333 - Biomedical Signals and Systems (3-0-3)
Prerequisites: BME 310 and Math 222. BME Tools such as the Laplace and Fourier Transforms, time-frequency analysis are introduced. Applications include signals and noise, processing of the ECG, mathematics of imaging and derivation of useful physiological parameters from input signals. Effective From: Fall 2006
BME 351 - Introduction to Biofluid Mechanics (3-0-3)
Prerequisites: BME 302 and Mech 236. Recommended co-requisite: Mech 320. Introduction to the principles of fluid flow. Basic fluid principles, such as fluid properties, fluid statics, conservation of mass, momentum, and energy will be discussed and presented in bioengineering context. Special attention will be given to the non-Newtonian nature of blood, viscous flow in arteries, unsteady flows, and to the fluidic output of the heart. The textbook material will be supplemented throughout the course to emphasize examples relative to bioengineering. Effective From: Spring 2007
BME 372 - Biomedical Electronics (3-0-3)
Prerequisite: BME 301. The first of a two-semester sequence. It covers the design of electronic circuits for Biomedical applications. This course covers basic operational amplifier circuits as well as the operation of semiconductor diodes and transistors. An introduction to digital logic circuits is also provided. Pspice computer simulation as well as hands-on breadboarding of electronic circuits are used throughout the course to supplement the lectures.
BME 373 - Biomedical Electronics II (3-0-3)
Prerequisite: BME 372. A continuation of BME 372 emphasizing biomedical applications of oscillators, active filters, and wave-shaping circuits.
BME 381 - Engineering Models in Physiology I (3-2-3)
Prerequisites: Math 222, BME 106 and Phys 121. Some knowledge of programming required. Mathematical models of organs and organ systems are described from an engineering viewpoint. Anatomy and physiology are quantified. Heart and circulation, gas exchange in the lungs, electrical properties of excitable membranes, renal countercurrent mechanism and muscle mechanics are among the topics covered. Emphasis will be placed on feedback control, mathematical modeling and numerical simulation. Effective From: Spring 2006
BME 382 - Engineering Models in Physiology II (3-2-3)
Prerequisites: Math 222, BME 106 and Phys 121. BME 381 is not a prerequisite. Some knowledge of programming required. Mathematical models of organs and organ systems are described from an engineering viewpoint. Anatomy and physiology are quantified. Heart and circulation, gas exchange in the lungs, electrical properties of excitable membranes, renal countercurrent mechanism and muscle mechanics are among the topics covered. Effective From: Spring 2006
BME 383 - Measurement Lab for Physiological Systems & Tissue (1-3-3)
Prerequisites: BME 105, BME 106, BME 302, BME 310. Through laboratory experiences, students will apply engineering methods for measuring and interpretating the properties of physiological systems and biological tissues. Topics include measurements relevant to cardio-pulmonary, nerve and muscular systems, and epithelial transport. Effective From: Spring 2008
BME 411 - Co-op Work Experience (3 additive credits)
Prerequisites: BME 311 and completion of sophomore year, approval of department, and permission of Career Development Services. Students gain major-related work experience and reinforcement of their academic program. Work assignments facilitated by the co-op office and approved by the department. Mandatory participation in seminars and completion of a report.
BME 420 - Biomaterials and Compatibility (3-0-3)
Prerequisites: Physics 121, Chemistry 126, Mech 320. An introduction to the field of biomaterials. The goal of this course is to understand material selection and the limitations imposed by current materials on device performance. The first part of the course will provide an overview of the current medical devices/implants with respect to their clinical relevance. Subsequently, the structure and properties of metals, ceramics, and polymers will be discussed. Properties include mechanical behavior, thermal, and surface characteristics. The second part of the course will discuss biocompatibility and implant design. Immunological and various histological responses will be described. Material properties of hard and soft tissues, their response to implants and the material selection for such tissues will be discussed.
BME 422 - Biomaterials Characterization (3-0-3)
Prerequisites: BME 420 or MTSE 301. The quantum mechanical origins of spectroscopy, the relationship of spectroscopic behavior to thermal characteristics of a material, and the differences in approach to the chemical and physical characterization of synthetic and biological polymers are discussed. Effective From: Spring 2007
BME 427 - Biotransport (3-0-3)
Prerequisite: Math 222 and CHE 230. Introduction to basic concepts in thermodynamics and transport phenomena as applied to biological systems. The structure and composition of the body will be covered followed by an exploration of the properties of the blood and its flow in the cardiovascular system, and the body as a heat source and as a series of compartments involved in the mass transfer of materials (such as those in the kidneys and lungs). Design of artificial kidneys and heart-lung machines is also explored.
BME 430 - Fundamentals of Tissue Engineering (3-0-3)
Prerequisite: BME 420. This course is an introduction to the field of tissue engineering as a therapeutic approach to treating damaged or diseased tissues in the biotechnology industry. In essence, new and functional living tissue can be fabricated by delivering cells, scaffolds, DNA, proteins, and/or protein fragments at surgery. This course will cover the advances in the fields of cell biology, molecular biology, material science and their relationship towards developing novel "tissue engineered" therapies. Effective From: Fall 2006
BME 451 - Biomechanics I (3-0-3)
Prerequisites: Mech 320 and BME 351. Tensor analysis. Kinematics of continuous media. Stress. The elastic solid. Newtonian fluid. Conservation principles of mass, momentum and energy. Viscometric flows. Formulation of constitutive equations. Applications to the modeling of bone and other living tissues. Effective From: Fall 2007
BME 452 - Biomechanics II (3-0-3)
Continuation of BME 451, Biomechanics I. The primary emphasis of this course is on physiological flows in the human body. Constitutive relations. Blood rheology. Flow in the microcirculation. Bernoulli's equation. Boundary layer theory. Lubrication theory. Pulse propagation and blood flow in the large arteries. Effective From: Spring 2007
BME 469 - Introduction to Human Physiology (3-0-3)
This course is not open to Biomedical Engineering students. Available to non-biomedical engineering students who have an interest in going on to medical, dental or allied health careers. An introduction to mammalian physiology, particularly the heart, circulation, lungs and kidneys. Effective Until: Fall 2003
BME 478 - Introduction to CAD for Biomechanics (2-2-3)
Prerequisites: BME 302 and Mech 320. Introduction to Computer Aided Designing and analysis as applied to biomedical engineering design programs. Topics include theoretical insight into the process of design and geometrical modeling and design using industry standard CAD (Computer Aided Design) software packages. The course will also include several projects involving the applicaiton of design principles to standard problems in biomedical design. Effective From: Spring 2007
BME 479 - BioMicroElectroMechanical Systems (3-0-3)
Prerequisites: Chem 126 and Phys 121. Knowledge of mechanics, optics, electromagnetism and general chemistry. Micro- and nanosystems used in advanced analytical techniques for microfluidic devices, implantable chips, non-invasive biomedical sensors, DNA chips and microelectronic array systems. Microelectronic processing design for micromaching and piezoelectric materials for biomedical applications. Biomedical sensors and actuators. BioMEMS active ultrasonic transducers for medical imaging, for micro-valves and for implantable medication delivery systems are studied.
BME 489 - Medical Instrumentation (3-0-3)
Prerequisites: BME 373, BME 310 and ECE 251. The hardware and instrumentation needed to measure variables from different physiological systems. Electrodes, sensors and transducers. Bioelectric amplifiers. Hardware for measurement of the ECG, EEG, EMG, respiratory system, nervous system . Clinical laboratory instruments. Medical ultrasound. Electrical safety. Computers in biomedical instrumentation.
BME 491 - Research and Independent Study I (1-0-1)
Needs permission of professor. Senior standing. Planning and execution of engineering projects. Intellectual property: publications and priority documents; invention disclosures and patents. Safety: engineering codes and standards. Engineering ethics. Professional organizations. Professional registration. Preparation of a technical proposal for a senior project and its approval are required.
BME 492 - Research and Independent Study II (1-2-3)
Needs permission of professor. A biomedical engineering design project, selected by the student, which has been approved in BME 491. Involves information from the professional literature, research, design and prototype testing. An oral presentation and a written report are required.
BME 495 - Capstone Design I (2-3-3)
Prerequisites: BME 372 or BME 420 or BME 351. Senior standing or permission of the instructor. To provide students with the guidance to choose a capstone design topic and advisor and to prepare the design proposal. The course introduces the student to the definition of design as well as introducing issues of intellectual property, bioethics and safety, and professional societies. Effective From: Fall 2008
BME 496 - Capstone Design 2 (2-5-3)
Prerequisites: BME 495 Implementation of the project approved in BME 491. This portion of the project includes library research, time and cost planning, oral and written reports, as well as construction, troubleshooting and demonstration of a working prototype. Effective From: Fall 2008
DEL_BME 102 - Survey of Human Physiology (1-0-1)
This course is open only to freshmen and new transfer students. An overview of human physiology is taught as an introduction to subsequent core courses in the Biomedical Engineering curriculum.
DEL_BME 314 - Biomedical Signals and Systems (3-0-3)
Prerequisites: Math 222 and BME 310. This course covers the mathematical tools required to analyze the signals and systems found in biomedical engineering. Tools such as the Laplace and Fourier Transforms, time-frequency analysis are introduced. Applications include signals and noise, mathematics of imaging and derivation of useful physiological parameters from input signals.
DEL_BME 402 - Biophotonics (0-3-3)
Prerequisites: Physics 121. A laboratory/studio style course in which the applications of light an electrical energy are explored to study the bodys normal surface characteristics and to diagnose medical problems related to aberrations of the surface. Interaction of light with biotissues. Measurement of tissue absorption and scattering. Fiber optics and endoscopy. Basics of laser surgery. Simulation of light propagation in tissues. Same as OPSE 310.
DEL_BME 467 - Pathophysiology of the Heart (3-0-3)
Prerequisites: BME 301, BME 302 and BME 303. This course addresses heart disease as an example of how biomedical engineering contributes to the diagnosis and management of patients. Topics include how the normal heart works and how diseases can disrupt normal heart function. Techniques used to measure cardiac function as well as treatments for common heart diseases such as acute myocardial infarction, heart failure and chronic ischemic heart disease are discussed. Student presentations are a major part of this course. Each student will be assigned a recent research paper in cardiology.
DEL_BME 474 - Biomechanics of Living Tissues: Solids (3-0-3)
Prerequisites: Math 222 and Mech 327. Measurements of deformation and strain resulting from stress on bone, muscle, spinal discs, cartilage, skin, blood vessels, etc.. Fiber reinforcement in tissues (anisotropy) and viscoelastic properties of tissues. Review of methods for testing and describing mechanical behavior of tissues. Long term adaptation of living tissues to mechanical environment (growth and atrophy). Overview of mechanics at the cellular level.
DEL_BME 476 - Physiological Mechanics of Fluids (3-0-3)
Prerequisites:Math 222 and BME 302. Newtonian and non-Newtonian fluid mechanics. Pulsatile flow, vortex control of valve motion, and regurgitation will be described. The thixotropic nature of blood. Shear-rate and time-dependent viscosity of blood. Other biological fluids such as mucous and spinal fluid will also be covered. Overview of airway flow in the lung and the effects of aerosols.
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